Coin is a written, valid and full content document that its investigation is essential from various aspects. Accordingly, the coins are one of the most important research tools and methods for recognition the history, culture and civilization that help to introduce and analyze the social, cultural, economic and political situations of each course.

In this study, the results of elemental analysis of 6 one Drachma coins of Khosrow II and 11 silver coins belong to Septimius and his wife Julia Domana by XRF method have been reported.

These results show a drop in purity percentage of silver in the Khosrow II coins and weight reduction in Septimius and his wife Julia Domana silver coins. The cause of these fluctuations must be searched in the beginning of 5 year war of Iran and Rome which led to defeat of the Persians and recapturing Cteisphon by Romans at the end of the year 197 AD.. The cause of these fluctuations must be searched in the beginning of 5 year war of Iran and Rome which led to defeat of the Persians and recapturing Cteisphon by Romans at the end of the year 197 AD